PDGF Upregulates Mcl-1 Through Activation of β-Catenin and HIF-1α-Dependent Signaling in Human Prostate Cancer Cells

BACKGROUND: Aberrant platelet derived growth factor (PDGF) signaling has been associated with prostate cancer (PCa) progression. However, its role in the regulation of PCa cell growth and survival has not been well characterized. METHODOLOGY/PRINCIPAL FINDINGS: Using experimental models that closely...

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Detaylı Bibliyografya
Asıl Yazarlar: Iqbal, Shareen, Zhang, Shumin, Driss, Adel, Liu, Zhi-Ren, Kim, Hyeong-Reh Choi, Wang, Yanru, Ritenour, Chad, Zhau, Haiyen E., Kucuk, Omer, Chung, Leland W. K., Wu, Daqing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262835/
https://ncbi.nlm.nih.gov/pubmed/22276222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030764
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