PDGF Upregulates Mcl-1 Through Activation of β-Catenin and HIF-1α-Dependent Signaling in Human Prostate Cancer Cells

BACKGROUND: Aberrant platelet derived growth factor (PDGF) signaling has been associated with prostate cancer (PCa) progression. However, its role in the regulation of PCa cell growth and survival has not been well characterized. METHODOLOGY/PRINCIPAL FINDINGS: Using experimental models that closely...

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Autores principales: Iqbal, Shareen, Zhang, Shumin, Driss, Adel, Liu, Zhi-Ren, Kim, Hyeong-Reh Choi, Wang, Yanru, Ritenour, Chad, Zhau, Haiyen E., Kucuk, Omer, Chung, Leland W. K., Wu, Daqing
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262835/
https://ncbi.nlm.nih.gov/pubmed/22276222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030764
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