HMGA1 Induces Intestinal Polyposis in Transgenic Mice and Drives Tumor Progression and Stem Cell Properties in Colon Cancer Cells

BACKGROUND: Although metastatic colon cancer is a leading cause of cancer death worldwide, the molecular mechanisms that enable colon cancer cells to metastasize remain unclear. Emerging evidence suggests that metastatic cells develop by usurping transcriptional networks from embryonic stem (ES) cel...

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Autors principals: Belton, Amy, Gabrovsky, Alexander, Bae, Young Kyung, Reeves, Ray, Iacobuzio-Donahue, Christine, Huso, David L., Resar, Linda M. S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262796/
https://ncbi.nlm.nih.gov/pubmed/22276142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030034
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