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Anti-CTLA4 monoclonal antibodies: the past and the future in clinical application

Recently, two studies using ipilimumab, an anti-CTLA-4 monoclonal antibody (mab) demonstrated improvements in overall survival in the treatment of advanced melanoma. These studies utilized two different schedules of treatment in different patient categories (first and second line of treatment). Howe...

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Détails bibliographiques
Auteurs principaux: Ascierto, Paolo A, Marincola, Francesco M, Ribas, Antoni
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262765/
https://ncbi.nlm.nih.gov/pubmed/22077981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-196
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