An Extracellular Signal–Regulated Kinase 2 Survival Pathway Mediates Resistance of Human Mesothelioma Cells to Asbestos-Induced Injury

We hypothesized that normal human mesothelial cells acquire resistance to asbestos-induced toxicity via induction of one or more epidermal growth factor receptor (EGFR)–linked survival pathways (phosphoinositol-3-kinase/AKT/mammalian target of rapamycin and extracellular signal–regulated kinase [ERK...

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Hlavní autoři: Shukla, Arti, Barrett, Trisha F., MacPherson, Maximilian B., Hillegass, Jedd M., Fukagawa, Naomi K., Swain, William A., O'Byrne, Kenneth J., Testa, Joseph R., Pass, Harvey I., Faux, Stephen P., Mossman, Brooke T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262687/
https://ncbi.nlm.nih.gov/pubmed/21454801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0282OC
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