ERK2 is Essential for the Growth of Human Epithelioid Malignant Mesotheliomas

Members of the extracellular signal-regulated kinase (ERK) family may have distinct roles in the development of cell injury and repair, differentiation and carcinogenesis. Here we show, using a synthetic small molecule MEK1/2 inhibitor (U0126) and RNA silencing of ERK1 and 2, comparatively, that ERK...

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Autori principali: Shukla, Arti, Hillegass, Jedd M., MacPherson, Maximilian B., Beuschel, Stacie L., Vacek, Pamela M., Butnor, Kelly J., Pass, Harvey I., Carbone, Michele, Testa, Joseph R., Heintz, Nicholas H., Mossman, Brooke T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071888/
https://ncbi.nlm.nih.gov/pubmed/21710492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25763
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