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Exocytosis from pancreatic β-cells: mathematical modelling of the exit of low-molecular-weight granule content

Pancreatic β-cells use Ca(2+)-dependent exocytosis of large dense core vesicles to release insulin. Exocytosis in β-cells has been studied biochemically, biophysically and optically. We have previously developed a biophysical method to monitor release of endogenous intragranular constituents that ar...

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Bibliographic Details
Main Authors: Galvanovskis, Juris, Braun, Matthias, Rorsman, Patrik
Format: Artigo
Language:Inglês
Published: The Royal Society 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262246/
https://ncbi.nlm.nih.gov/pubmed/22419980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2010.0006
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