Transient decrease in tumor oxygenation after intravenous administration of pyruvate

MRI using hyperpolarized (13)C-labeled pyruvate is a promising tool to biochemically profile tumors and monitor their response to therapy. This technique requires injection of pyruvate into tumor-bearing animals. Pyruvate is an endogenous entity but the influence of exogenously injected bolus doses...

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Bibliographic Details
Main Authors: Saito, Keita, Matsumoto, Shingo, Devasahayam, Nallathamby, Subramanian, Sankaran, Munasinghe, Jeeva P., Morris, H. Douglas, Lizak, Martin J., Ardenkjaer-Larsen, Jan Henrik, Mitchell, James B., Krishna, Murali C.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262125/
https://ncbi.nlm.nih.gov/pubmed/22006570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.23065
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