Rap1-Rac1 Circuits Potentiate Platelet Activation

OBJECTIVE: The goal of this study was to investigate the potential crosstalk between Rap1 and Rac1, 2 small GTPases central to platelet activation, particularly downstream of the collagen receptor GPVI. METHODS AND RESULTS: We compared the activation response of platelets with impaired Rap signaling...

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Hoofdauteurs: Stefanini, Lucia, Boulaftali, Yacine, Ouellette, Timothy D., Holinstat, Michael, Désiré, Laurent, Leblond, Bertrand, Andre, Patrick, Conley, Pamela B., Bergmeier, Wolfgang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262085/
https://ncbi.nlm.nih.gov/pubmed/22075250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.239194
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