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Rap1-Rac1 Circuits Potentiate Platelet Activation
OBJECTIVE: The goal of this study was to investigate the potential crosstalk between Rap1 and Rac1, 2 small GTPases central to platelet activation, particularly downstream of the collagen receptor GPVI. METHODS AND RESULTS: We compared the activation response of platelets with impaired Rap signaling...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262085/ https://ncbi.nlm.nih.gov/pubmed/22075250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.239194 |
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