Pharmacologic Suppression of Hepcidin Increases Macrophage Cholesterol Efflux and Reduces Foam Cell Formation and Atherosclerosis

OBJECTIVES: We recently reported that lowering of macrophage free intracellular iron increases expression of cholesterol efflux transporters ABCA1 and ABCG1 by reducing generation of reactive oxygen species. In this study, we explore whether reducing macrophage intracellular iron levels via pharmaco...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Saeed, Omar, Otsuka, Fumiyuki, Polavarapu, Rohini, Karmali, Vinit, Weiss, Daiana, Davis, Talina, Rostad, Brad, Pachura, Kimberly, Adams, Lila, Elliott, John, Taylor, W. Robert, Narula, Jagat, Kolodgie, Frank, Virmani, Renu, Hong, Charles C., Finn, Aloke V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262074/
https://ncbi.nlm.nih.gov/pubmed/22095982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.240101
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados