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Specific domains of nucleolin interact with Hdm2 and antagonize Hdm2-mediated p53-ubiquitination

Nucleolin is an abundant multifunctional nucleolar protein with defined roles in ribosomal RNA processing, RNA polymerase I-catalyzed transcription, and the regulation of apoptosis. Earlier we reported that human nucleolin binds to the p53-antagonist Hdm2 as determined by reciprocal co-immunoprecipi...

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Bibliografische gegevens
Hoofdauteurs: Bhatt, Purvi, d’Avout, Claire, Kane, Naomi S., Borowiec, James A., Saxena, Anjana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262062/
https://ncbi.nlm.nih.gov/pubmed/22103682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2011.08430.x
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