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Ectopic Wnt/Beta–Catenin Signaling Induces Neurogenesis in the Spinal Cord and Hindbrain Floor Plate

The most ventral structure of the developing neural tube, the floor plate (FP), differs in neurogenic capacity along the neuraxis. The FP is largely non-neurogenic at the hindbrain and spinal cord levels, but generates large numbers of dopamine (mDA) neurons at the midbrain levels. Wnt1, and other W...

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Autori principali: Joksimovic, Milan, Patel, Meera, Taketo, Makoto Mark, Johnson, Randy, Awatramani, Rajeshwar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261891/
https://ncbi.nlm.nih.gov/pubmed/22276170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030266
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