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Ectopic Wnt/Beta–Catenin Signaling Induces Neurogenesis in the Spinal Cord and Hindbrain Floor Plate

The most ventral structure of the developing neural tube, the floor plate (FP), differs in neurogenic capacity along the neuraxis. The FP is largely non-neurogenic at the hindbrain and spinal cord levels, but generates large numbers of dopamine (mDA) neurons at the midbrain levels. Wnt1, and other W...

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Detalhes bibliográficos
Main Authors: Joksimovic, Milan, Patel, Meera, Taketo, Makoto Mark, Johnson, Randy, Awatramani, Rajeshwar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261891/
https://ncbi.nlm.nih.gov/pubmed/22276170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030266
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