Excessive Wnt/beta–catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors

The floor plate (FP), a ventral midline structure of the developing neural tube, has differential neurogenic capabilities along the anterior-posterior axis. The midbrain FP, unlike the hindbrain and spinal cord floor plate, is highly neurogenic and produces midbrain dopaminergic (mDA) neurons. Canon...

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Pubblicato in:Mol Cell Neurosci
Autori principali: Nouri, Navid, Patel, Meera J., Joksimovic, Milan, Poulin, Jean-Francois, Anderegg, Angela, Taketo, M. Mark, Ma, Yong-Chao, Awatramani, Rajeshwar
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633300/
https://ncbi.nlm.nih.gov/pubmed/26164566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2015.07.002
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