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Two-Dimensional IR Spectroscopy of Protein Dynamics Using Two Vibrational Labels: A Site-Specific Genetically Encoded Unnatural Amino Acid and an Active Site Ligand

[Image: see text] Protein dynamics and interactions in myoglobin (Mb) were characterized via two vibrational dynamics labels (VDLs): a genetically incorporated site-specific azide (Az) bearing unnatural amino acid (AzPhe43) and an active site CO ligand. The Az-labeled protein was studied using ultra...

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Main Authors: Thielges, Megan C., Axup, Jun Y., Wong, Daryl, Lee, Hyun Soo, Chung, Jean K., Schultz, Peter G., Fayer, Michael D.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261801/
https://ncbi.nlm.nih.gov/pubmed/21823631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp206986v
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