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Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

Genetic analysis in Drosophila melanogaster has been widely used to identify a system of genes that control cell growth in response to insulin and nutrients. Many of these genes encode components of the insulin receptor/target of rapamycin (InR/TOR) pathway. However, the biochemical context of this...

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Main Authors: Glatter, Timo, Schittenhelm, Ralf B, Rinner, Oliver, Roguska, Katarzyna, Wepf, Alexander, Jünger, Martin A, Köhler, Katja, Jevtov, Irena, Choi, Hyungwon, Schmidt, Alexander, Nesvizhskii, Alexey I, Stocker, Hugo, Hafen, Ernst, Aebersold, Ruedi, Gstaiger, Matthias
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261712/
https://ncbi.nlm.nih.gov/pubmed/22068330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.79
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