Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

Genetic analysis in Drosophila melanogaster has been widely used to identify a system of genes that control cell growth in response to insulin and nutrients. Many of these genes encode components of the insulin receptor/target of rapamycin (InR/TOR) pathway. However, the biochemical context of this...

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Detalhes bibliográficos
Main Authors: Glatter, Timo, Schittenhelm, Ralf B, Rinner, Oliver, Roguska, Katarzyna, Wepf, Alexander, Jünger, Martin A, Köhler, Katja, Jevtov, Irena, Choi, Hyungwon, Schmidt, Alexander, Nesvizhskii, Alexey I, Stocker, Hugo, Hafen, Ernst, Aebersold, Ruedi, Gstaiger, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261712/
https://ncbi.nlm.nih.gov/pubmed/22068330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.79
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