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The proline TP53 variant stimulates likely lymphangiogenesis in an orthotopic mouse model of pancreatic cancer

BACKGROUND: Pancreatic cancer is a deadly disease characterised by high incidence of TP53 mutations. Restoration of TP53 function is perceived as a highly attractive therapeutic strategy, whose effects are not well characterised. METHODS: The current work adapted an inducible strategy of stage-speci...

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Bibliografische gegevens
Hoofdauteurs: Otto, N, Schulz, P, Scholz, A, Hauff, P, Schlegelberger, B, Detjen, K M, Wiedenmann, B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261666/
https://ncbi.nlm.nih.gov/pubmed/22146521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.521
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