Human tRNA genes function as chromatin insulators

Insulators help separate active chromatin domains from silenced ones. In yeast, gene promoters act as insulators to block the spread of Sir and HP1 mediated silencing while in metazoans most insulators are multipartite autonomous entities. tDNAs are repetitive sequences dispersed throughout the huma...

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Detaylı Bibliyografya
Asıl Yazarlar: Raab, Jesse R, Chiu, Jonathan, Zhu, Jingchun, Katzman, Sol, Kurukuti, Sreenivasulu, Wade, Paul A, Haussler, David, Kamakaka, Rohinton T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261562/
https://ncbi.nlm.nih.gov/pubmed/22085927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.406
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