An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment

The role of DNA sequence in determining chromatin state is incompletely understood. We have previously demonstrated that large chromosomal segments from human cells recapitulate their native chromatin state in mouse cells, but the relative contribution of local sequences versus their genomic context...

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Bibliographic Details
Main Authors: Lynch, Magnus D, Smith, Andrew J H, De Gobbi, Marco, Flenley, Maria, Hughes, Jim R, Vernimmen, Douglas, Ayyub, Helena, Sharpe, Jacqueline A, Sloane-Stanley, Jacqueline A, Sutherland, Linda, Meek, Stephen, Burdon, Tom, Gibbons, Richard J, Garrick, David, Higgs, Douglas R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261560/
https://ncbi.nlm.nih.gov/pubmed/22056776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.399
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