Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria

Covalent modification of proteins with ubiquitin (Ub) is widely implicated in the control of protein function and fate. Over 100 deubiquitylating enzymes rapidly reverse this modification, posing challenges to the biochemical and biophysical characterization of ubiquitylated proteins. We circumvente...

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Detalhes bibliográficos
Principais autores: Keren-Kaplan, Tal, Attali, Ilan, Motamedchaboki, Khatereh, Davis, Brian A, Tanner, Neta, Reshef, Yael, Laudon, Einat, Kolot, Mikhail, Levin-Kravets, Olga, Kleifeld, Oded, Glickman, Michael, Horazdovsky, Bruce F, Wolf, Dieter A, Prag, Gali
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261559/
https://ncbi.nlm.nih.gov/pubmed/22081111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.397
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