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Role of JNK in mammary gland development and breast cancer

JNK signaling has been implicated in the developmental morphogenesis of epithelial organs. In this study we employed a compound deletion of the murine Jnk1 and Jnk2 genes in the mammary gland to evaluate the requirement for these ubiquitously expressed genes in breast development and tumorigenesis....

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Hlavní autoři: Cellurale, Cristina, Girnius, Nomeda, Jiang, Feng, Cavanagh-Kyros, Julie, Lu, Shaolei, Garlick, David S., Mercurio, Arthur M., Davis, Roger J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261359/
https://ncbi.nlm.nih.gov/pubmed/22127926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1628
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