Rapid Evaluation in Whole Blood Culture of Regimens for XDR-TB Containing PNU-100480 (Sutezolid), TMC207, PA-824, SQ109, and Pyrazinamide

There presently is no rapid method to assess the bactericidal activity of new regimens for tuberculosis. This study examined PNU-100480, TMC207, PA-824, SQ109, and pyrazinamide, singly and in various combinations, against intracellular M. tuberculosis, using whole blood culture (WBA). The addition o...

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Autors principals: Wallis, Robert S., Jakubiec, Wesley, Mitton-Fry, Mark, Ladutko, Lynn, Campbell, Sheldon, Paige, Darcy, Silvia, Annette, Miller, Paul F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261206/
https://ncbi.nlm.nih.gov/pubmed/22279595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030479
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