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Brain region-specific expression of Fxyd1, a Mecp2 target gene, is regulated by epigenetic mechanisms

Fxyd1 encodes a trans-membrane protein that modulates Na(+), K(+)-ATPase activity and is a substrate for multiple protein kinases. Fxyd1 expression is repressed by methyl CpG-binding protein 2 (Mecp2) in the frontal cortex (FC), but not in the cerebellum (CB) of the mouse brain. Consistent with thes...

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Detalhes bibliográficos
Main Authors: Banine, Fatima, Matagne, Valerie, Sherman, Larry S., Ojeda, Sergio R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261072/
https://ncbi.nlm.nih.gov/pubmed/21394759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22608
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