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Epigenetic remodelling of Fxyd1 promoters in developing heart and brain tissues
Abstract FXYD1 is a key protein controlling ion channel transport. FXYD1 exerts its function by regulating Na+/K+-ATPase activity, mainly in brain and cardiac tissues. Alterations of the expression level of the FXYD1 protein cause diastolic dysfunction and arrhythmias in heart and decreased neuronal...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Portfolio
2022-04-01
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Colecção: | Scientific Reports |
Acesso em linha: | https://doi.org/10.1038/s41598-022-10365-y |
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