5-Fluorouracil-loaded poly(ε-caprolactone) nanoparticles combined with phage E gene therapy as a new strategy against colon cancer

This work aimed to develop a new therapeutic approach to increase the efficacy of 5-fluorouracil (5-FU) in the treatment of advanced or recurrent colon cancer. 5-FU-loaded biodegradable poly(ε-caprolactone) nanoparticles (PCL NPs) were combined with the cytotoxic suicide gene E (combined therapy). T...

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Detalhes bibliográficos
Main Authors: Ortiz, Raúl, Prados, José, Melguizo, Consolación, Arias, José L, Ruiz, M Adolfina, Álvarez, Pablo J, Caba, Octavio, Luque, Raquel, Segura, Ana, Aránega, Antonia
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260954/
https://ncbi.nlm.nih.gov/pubmed/22275826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S26401
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