Expression of the IGF Axis Is Decreased in Local Prostate Cancer but Enhanced after Benign Prostate Epithelial Differentiation and TGF-β Treatment

The insulin-like growth factor (IGF) axis is a molecular pathway intensively investigated in cancer research. Clinical trials targeting the IGF1 receptor (IGF1R) in different tumors, including prostate cancer, are under way. Although studies on the IGF axis in prostate cancer have already entered in...

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Bibliographic Details
Main Authors: Massoner, Petra, Ladurner Rennau, Michael, Heidegger, Isabel, Kloss-Brandstätter, Anita, Summerer, Monika, Reichhart, Eva, Schäfer, Georg, Klocker, Helmut
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2011
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260840/
https://ncbi.nlm.nih.gov/pubmed/21983635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.08.026
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