Both IGF1R and INSR Knockdown Exert Antitumorigenic Effects in Prostate Cancer In Vitro and In Vivo

The IGF network with its main receptors IGF receptor 1 (IGF1R) and insulin receptor (INSR) is of major importance for cancer initiation and progression. To date, clinical studies targeting this network were disappointing and call for thorough analysis of the IGF network in cancer models. We highligh...

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發表在:Mol Endocrinol
Main Authors: Ofer, Philipp, Heidegger, Isabel, Eder, Iris E., Schöpf, Bernd, Neuwirt, Hannes, Geley, Stephan, Klocker, Helmut, Massoner, Petra
格式: Artigo
語言:Inglês
出版: Endocrine Society 2015
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669362/
https://ncbi.nlm.nih.gov/pubmed/26452103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1073
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