Both IGF1R and INSR Knockdown Exert Antitumorigenic Effects in Prostate Cancer In Vitro and In Vivo

The IGF network with its main receptors IGF receptor 1 (IGF1R) and insulin receptor (INSR) is of major importance for cancer initiation and progression. To date, clinical studies targeting this network were disappointing and call for thorough analysis of the IGF network in cancer models. We highligh...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Ofer, Philipp, Heidegger, Isabel, Eder, Iris E., Schöpf, Bernd, Neuwirt, Hannes, Geley, Stephan, Klocker, Helmut, Massoner, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669362/
https://ncbi.nlm.nih.gov/pubmed/26452103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1073
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