Both IGF1R and INSR Knockdown Exert Antitumorigenic Effects in Prostate Cancer In Vitro and In Vivo

The IGF network with its main receptors IGF receptor 1 (IGF1R) and insulin receptor (INSR) is of major importance for cancer initiation and progression. To date, clinical studies targeting this network were disappointing and call for thorough analysis of the IGF network in cancer models. We highligh...

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Dettagli Bibliografici
Pubblicato in:Mol Endocrinol
Autori principali: Ofer, Philipp, Heidegger, Isabel, Eder, Iris E., Schöpf, Bernd, Neuwirt, Hannes, Geley, Stephan, Klocker, Helmut, Massoner, Petra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2015
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669362/
https://ncbi.nlm.nih.gov/pubmed/26452103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1073
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