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Insulin-like growth factors and insulin control a multifunctional signalling network of significant importance in cancer

Insulin-like growth factor (IGF) and insulin (INS) proteins regulate key cellular functions through a complex interacting multi-component molecular network, known as the IGF/INS axis. We describe how dynamic and multilayer interactions give rise to the multifunctional role of the IGF/INS axis. Furth...

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Detalhes bibliográficos
Main Authors: Massoner, P, Ladurner-Rennau, M, Eder, I E, Klocker, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990579/
https://ncbi.nlm.nih.gov/pubmed/20924377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605932
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