Focal Adhesion Kinase Signaling Mediates Acute Renal Injury Induced by Ischemia/Reperfusion

Renal ischemia/reperfusion (I/R) injury is associated with cell matrix and focal adhesion remodeling. Focal adhesion kinase (FAK) is a nonreceptor protein tyrosine kinase that localizes at focal adhesions and regulates their turnover. Here, we investigated the role of FAK in renal I/R injury, using...

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Detalhes bibliográficos
Main Authors: Qin, Yu, Alderliesten, Maaike C., Stokman, Geurt, Pennekamp, Petra, Bonventre, Joseph V., de Heer, Emile, Ichimura, Takaharu, de Graauw, Marjo, Price, Leo S., van de Water, Bob
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260828/
https://ncbi.nlm.nih.gov/pubmed/21982831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.08.025
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