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Monomeric α-Synuclein Binds Congo Red Micelles in a Disordered Manner

[Image: see text] The histological dye Congo Red (CR) previously has been shown to inhibit α-synuclein (aS) fibrillation, but the mode of this inhibition remained unclear. Because of favorable exchange kinetics, interaction between CR and aS lends itself to a detailed nuclear magnetic resonance stud...

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Détails bibliographiques
Auteurs principaux: Maltsev, Alexander S., Grishaev, Alexander, Bax, Ad
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2011
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260784/
https://ncbi.nlm.nih.gov/pubmed/22242826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201435d
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