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Differential Phospholipid Binding of α-Synuclein Variants Implicated in Parkinson’s Disease Revealed by Solution NMR Spectroscopy
[Image: see text] Three familial variants of the presynaptic protein α-synuclein (αS), A30P, E46K, and A53T, correlate with rare inherited Parkinson’s disease (PD), while wild-type αS is implicated in sporadic PD. The classic manifestation of both familiar and sporadic PD is the formation of fibrill...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2815556/ https://ncbi.nlm.nih.gov/pubmed/20041693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901723p |
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