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Quantifying the Rheological and Hemodynamic Characteristics of Sickle Cell Anemia

Sickle erythrocytes exhibit abnormal morphology and membrane mechanics under deoxygenated conditions due to the polymerization of hemoglobin S. We employed dissipative particle dynamics to extend a validated multiscale model of red blood cells (RBCs) to represent different sickle cell morphologies b...

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Sonraí Bibleagrafaíochta
Main Authors: Lei, Huan, Karniadakis, George Em
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260690/
https://ncbi.nlm.nih.gov/pubmed/22339854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.12.006
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