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Quantifying the Rheological and Hemodynamic Characteristics of Sickle Cell Anemia
Sickle erythrocytes exhibit abnormal morphology and membrane mechanics under deoxygenated conditions due to the polymerization of hemoglobin S. We employed dissipative particle dynamics to extend a validated multiscale model of red blood cells (RBCs) to represent different sickle cell morphologies b...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3260690/ https://ncbi.nlm.nih.gov/pubmed/22339854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.12.006 |
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