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Predicting the morphology of sickle red blood cells using coarse-grained models of intracellular aligned hemoglobin polymers()

Sickle red blood cells (SS-RBCs) exhibit heterogeneous cell morphologies (sickle, holly leaf, granular, etc.) in the deoxygenated state due to the polymerization of the sickle hemoglobin. Experimental evidence points to a close relationship between SS-RBC morphology and intracellular aligned hemoglo...

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Detalhes bibliográficos
Main Authors: Lei, Huan, Karniadakis, George Em
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846403/
https://ncbi.nlm.nih.gov/pubmed/24307912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2SM07294G
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