Loading...

Genetically enhanced asynapsis of autosomal chromatin promotes transcriptional dysregulation and meiotic failure

During meiosis, pairing of homologous chromosomes and their synapsis are essential prerequisites for normal male gametogenesis. Even limited autosomal asynapsis often leads to spermatogenic impairment, the mechanism of which is not fully understood. The present study was aimed at deliberately increa...

Full description

Saved in:
Bibliographic Details
Main Authors: Homolka, David, Jansa, Petr, Forejt, Jiri
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260437/
https://ncbi.nlm.nih.gov/pubmed/22002499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-011-0346-5
Tags: Add Tag
No Tags, Be the first to tag this record!