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Genetically enhanced asynapsis of autosomal chromatin promotes transcriptional dysregulation and meiotic failure

During meiosis, pairing of homologous chromosomes and their synapsis are essential prerequisites for normal male gametogenesis. Even limited autosomal asynapsis often leads to spermatogenic impairment, the mechanism of which is not fully understood. The present study was aimed at deliberately increa...

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Detalhes bibliográficos
Main Authors: Homolka, David, Jansa, Petr, Forejt, Jiri
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260437/
https://ncbi.nlm.nih.gov/pubmed/22002499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-011-0346-5
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