Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice

Hybrid sterility is one of the reproductive isolation mechanisms leading to speciation. Prdm9, the only known vertebrate hybrid-sterility gene, causes failure of meiotic chromosome synapsis and infertility in male hybrids that are the offspring of two mouse subspecies. Within species, Prdm9 determin...

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Publicat a:eLife
Autors principals: Gregorova, Sona, Gergelits, Vaclav, Chvatalova, Irena, Bhattacharyya, Tanmoy, Valiskova, Barbora, Fotopulosova, Vladana, Jansa, Petr, Wiatrowska, Diana, Forejt, Jiri
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Chromosomes and Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902161/
https://ncbi.nlm.nih.gov/pubmed/29537370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34282
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