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Deducing the Temporal Order of Cofactor Function in Ligand-Regulated Gene Transcription: Theory and Experimental Verification

Cofactors are intimately involved in steroid-regulated gene expression. Two critical questions are (1) the steps at which cofactors exert their biological activities and (2) the nature of that activity. Here we show that a new mathematical theory of steroid hormone action can be used to deduce the k...

詳細記述

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書誌詳細
主要な著者: Dougherty, Edward J., Guo, Chunhua, Simons, S. Stoney, Chow, Carson C.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260260/
https://ncbi.nlm.nih.gov/pubmed/22272313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030225
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