Dominant-Negative Androgen Receptor Inhibition of Intracrine Androgen-Dependent Growth of Castration-Recurrent Prostate Cancer

BACKGROUND: Prostate cancer (CaP) is the second leading cause of cancer death in American men. Androgen deprivation therapy is initially effective in CaP treatment, but CaP recurs despite castrate levels of circulating androgen. Continued expression of the androgen receptor (AR) and its ligands has...

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Detalhes bibliográficos
Main Authors: Titus, Mark A., Zeithaml, Brian, Kantor, Boris, Li, Xiangping, Haack, Karin, Moore, Dominic T., Wilson, Elizabeth M., Mohler, James L., Kafri, Tal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260230/
https://ncbi.nlm.nih.gov/pubmed/22272301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030192
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