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Antibody degradation in tobacco plants: a predominantly apoplastic process

BACKGROUND: Interest in using plants for production of recombinant proteins such as monoclonal antibodies is growing, but proteolytic degradation, leading to a loss of functionality and complications in downstream purification, is still a serious problem. RESULTS: In this study, we investigated the...

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Detalhes bibliográficos
Main Authors: Hehle, Verena K, Paul, Matthew J, Drake, Pascal M, Ma, Julian KC, van Dolleweerd, Craig J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260137/
https://ncbi.nlm.nih.gov/pubmed/22208820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-128
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