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Characterization of the Conformational Epitope of Guy's 13, a Monoclonal Antibody That Prevents Streptococcus mutans Colonization in Humans

Guy's 13 is a mouse monoclonal antibody which recognizes streptococcal antigen I/II (SA I/II), a major cell surface glycoprotein of Streptococcus mutans. In a number of clinical trials, this antibody has been shown to prevent colonization in the human oral cavity. The aim of this study was to i...

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Autori principali: van Dolleweerd, Craig J., Chargelegue, Daniel, Ma, Julian K.-C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC145350/
https://ncbi.nlm.nih.gov/pubmed/12540555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.2.754-765.2003
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