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Characterization of the Conformational Epitope of Guy's 13, a Monoclonal Antibody That Prevents Streptococcus mutans Colonization in Humans

Guy's 13 is a mouse monoclonal antibody which recognizes streptococcal antigen I/II (SA I/II), a major cell surface glycoprotein of Streptococcus mutans. In a number of clinical trials, this antibody has been shown to prevent colonization in the human oral cavity. The aim of this study was to identi...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: van Dolleweerd, Craig J., Chargelegue, Daniel, Ma, Julian K.-C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145350/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12540555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.2.754-765.2003
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