Characterization of the Conformational Epitope of Guy's 13, a Monoclonal Antibody That Prevents Streptococcus mutans Colonization in Humans

Guy's 13 is a mouse monoclonal antibody which recognizes streptococcal antigen I/II (SA I/II), a major cell surface glycoprotein of Streptococcus mutans. In a number of clinical trials, this antibody has been shown to prevent colonization in the human oral cavity. The aim of this study was to identi...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	van Dolleweerd, Craig J., Chargelegue, Daniel, Ma, Julian K.-C.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Microbial Immunity and Vaccines
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145350/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12540555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.2.754-765.2003
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