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Site-targeted mutagenesis for stabilization of recombinant monoclonal antibody expressed in tobacco (Nicotiana tabacum) plants

This study examined the degradation pattern of a murine IgG1κ monoclonal antibody expressed in and extracted from transformed Nicotiana tabacum. Gel electrophoresis of leaf extracts revealed a consistent pattern of recombinant immunoglobulin bands, including intact and full-length antibody, as well...

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Bibliografski detalji
Izdano u:FASEB J
Glavni autori: Hehle, Verena K., Paul, Matthew J., Roberts, Victoria A., van Dolleweerd, Craig J., Ma, Julian K.-C.
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799508/
https://ncbi.nlm.nih.gov/pubmed/26712217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-283226
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