Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice

BACKGROUND: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) with unknown etiology. Interferon-β (IFN-β), a member of the type I IFN family, is used as a therapeutic for MS and the IFN signaling pathway is implicated in MS susceptibility. Interferon regulatory f...

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Autors principals: Salem, Mohammad, Mony, Jyothi T, Løbner, Morten, Khorooshi, Reza, Owens, Trevor
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260126/
https://ncbi.nlm.nih.gov/pubmed/22196084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-181
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