Interferon regulatory factor (IRF) 3 is critical for the development of experimental autoimmune encephalomyelitis

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) is an animal model of autoimmune inflammatory demyelination that is mediated by Th1 and Th17 cells. The transcription factor interferon regulatory factor 3 (IRF3) is activated by pathogen recognition receptors and induces interferon-β produ...

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Gepubliceerd in:J Neuroinflammation
Hoofdauteurs: Fitzgerald, Denise C, O’Brien, Kate, Young, Andrew, Fonseca-Kelly, Zoe, Rostami, Abdolmohamad, Gran, Bruno
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237888/
https://ncbi.nlm.nih.gov/pubmed/25069698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-130
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