Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis

The Type I interferons (IFN), beta (IFN-β) and the alpha family (IFN-α), act through a common receptor and have anti-inflammatory effects. IFN-β is used to treat multiple sclerosis (MS) and is effective against experimental autoimmune encephalomyelitis (EAE), an animal model for MS. Mice with EAE sh...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Khorooshi, Reza, Mørch, Marlene Thorsen, Holm, Thomas Hellesøe, Berg, Carsten Tue, Dieu, Ruthe Truong, Dræby, Dina, Issazadeh-Navikas, Shohreh, Weiss, Siegfried, Lienenklaus, Stefan, Owens, Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469095/
https://ncbi.nlm.nih.gov/pubmed/25869642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1418-z
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