Recombinant Modified Vaccinia Virus Ankara (MVA) Expressing Wild-Type Human p53 Induces Specific Antitumor CTL Expansion

The p53 gene product is an attractive target for tumor immunotherapy. The present study aims to understand the potential of MVAp53 vaccine to induce expansion of p53-specific cytotoxic T lymphocyte ex vivo in cancer patients. The result indicated that 14 of 23 cancer patients demonstrated p53-specif...

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Detalhes bibliográficos
Main Authors: Song, Guang-Yun, Srivastava, Tumul, Ishizaki, Hidenobu, Lacey, Simon F., Diamond, Don J., Ellenhorn, Joshua D. I.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2011
Assuntos:
Cellular and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260009/
https://ncbi.nlm.nih.gov/pubmed/21843052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/07357907.2011.606248
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